The Palestinian government has accused Israel of committing a 'terrible massacre' in Gaza. Gaza health officials say the number of Palestinians killed by Israeli army fire on the border has risen to 37, dozens were wounded, at the protests against opening the US embassy in the occupied Jerusalem get under way.
With the number dead reaching 37, today has become the deadliest day in the area since the 2014 Gaza war with Israel.
The brunt of the clashes is centred on the Gaza border, although a second clash was reported between Jerusalem and Bethlehem. There were no immediate reports of injuries in this second location.
"An immediate international intervention to stop the terrible massacre in Gaza committed by the forces of the Israeli occupation against our heroic people," has been called for by Palestinian government spokesman Yusuf al-Mahmoud.
Today marks the biggest showdown in recent weeks between Israel's military and Gaza's Hamas rulers along the volatile border.
Several thousand people are gathered in the centre of Ramallah, while hundreds have marched to the Qalandiya crossing on the outskirts of Jerusalem.
More than 500 have been injured and the death toll approaches twenty dead.
Israel says it only opens fire when necessary to stop infiltrations, attacks and damage to the border fence, while accusing Hamas, the Islamist movement that runs the blockaded Gaza Strip, of seeking to use the protests as cover to carry out violence.
Israeli military spokesman Lt Col Jonathan Conricus says the army has bolstered its front-line forces along the border, but also set up additional "layers" of security in and around neighbouring communities to defend Israeli civilians in case of a mass breach. He said there had already been several "significant attempts" to break through the fence.
"Even if the fence is breached, we will be able to protect Israeli civilians from attempts to massacre or kidnap or kill them," he said.